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| Abstract: The use of silver is increasing rapidly in the management of infected wounds and wounds at risk for infection. This 5-patient case series reviews the results of a pilot study designed to determine efficacy and safety of negative pressure wound therapy (NPWT; V.A.C.® Therapy™, KCI, San Antonio, Tex) with the new silver foam dressing (V.A.C.® GranuFoam® Silver™ Dressing, KCI). Data on wound progression and the primary endpoints—time to clear infection, time to wound closure, and time to discharge from hospital—are detailed in this manuscript. For the 5 patients treated with NPWT and the silver foam dressing, the mean time for treatment was 13.00 ± 3.39 days and the mean time to patient discharge was 16.00 ± 6.63 days. Wounds were clear of clinical signs of infection in 7.00 ± 1.58 days and closed in 19.20 ± 8.76 days.
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