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V.A.C.® Therapy Clinical Journal Abstracts Page
V.A.C.® Therapy Clinical Journal Abstracts Page
With over 300 peer-reviewed journal articles published, V.A.C.® Therapy has one of the largest bodies of evidence behind it.  Below you can find a small sample of these articles sorted by wound type.  Click on the citation, and the abstract will pop up for you to read. 
 
 
Acute Wounds
M. Kaplan. Abdominal Compartment Syndrome. Ostomy Wound Management, 2004; 50(4A-Suppl): 20-21.

Kaplan M., Banwell P., Orgill D., Ivatury R., Demitriades D., Moore F., Miller P., Nicholes J., Henry S., Guidelines for the Management of the Open Abdomen, Supplement to Wounds: A Compendium of Clinical Research and Practice, October 2005.

Krasner DL. Managing wound pain in patients with vacuum-assisted closure devices. Ostomy Wound Management, 2002; 48(5): 38-43.

Vishal Saxena, S.M., Dennis P Orgill, MD PhD. et al. Vacuum-Assisted Closure: Microdeformations of Wounds and Cell Proliferation. Plastic and Reconstructive Surgery 2004; 114(5): 1086-1096

Morykwas MJ, Argenta LC, Shelton-Brown EI, McGuirt W. Vacuum Assisted Closure: A new method for wound control and treatment: Animal studies and basic foundation. Annals of Plastic Surgery. 1997 June:38(6):553-62.

Morykwas MJ, Kennedy A, Argenta JP, Argenta LC. Use of subatmospheric pressure to prevent doxorubicin extravasation ulcers in a swine model. Journal of Surgical Oncology, 1999; 72: 14-17.

Mendez-Eastman S. Guidelines for using negative pressure wound therapy. Advances in Skin & Wound Care, 2001 Nov/Dec;14(6):314-25.

Meara JG, Guo L, Smith JD, Pribaz JJ, Breuing KH, Orgill DP. Vacuum-Assisted Closure in the treatment of degloving injuries. Annals of Plastic Surgery, 1999; 42(6): 589-94.

Chantal M. Moues, et. al. An Economic Evaluation of the use of TNP on full-thickness wounds. Journal of Wound Care Vol. 14, NO 5, page 1-6 May 2005.

Bookout K, McCord S, McLane K. Case studies of an infant, a toddler, and an adolescent treated with a negative pressure wound treatment system. JWOCN, 2004; 31(4): 184-192.

Yuan-Innes MJ, Temple CLF, Lacey MS. Vacuum-assisted wound closure: A new approach to spinal wounds with exposed hardware.Spine, 2001; 26(3):E30-33

Fabian TS, Kaufman HJ, Lett ED, Thomas JB, Rawl DK, Lewis PL,Summitt JB, Merryman JI, Schaeffer TD, Sargent LA, Burns RP. The evaluation of subatmospheric pressure and hyperbaric oxygen in ischemicfull-thickness wound healing. The American Surgeon. 2000 Dec;66(12):1136-43.

Orgill DP, Austen WG, Butler CE, Fine NA, Horvath KA, Mihaljevic T, Song DH, Wolfe WG. Guidelines for treatment of complex chest wounds with negative pressure wound therapy. WOUNDS. 2004 Dec;16(Suppl B): 1-23.

Tang ATM, Ohri SK, Haw MP. Novel application of vacuum assistedclosure technique to the treatment of sternotomy wound infection.European Journal of Cardio-Thoracic Surgery, 2000;17:482-4.

Agarwal JP, Ogilvie M, Wu LC, Lohman RF, Gottlieb LJ, Franczyk M, Song DH. Vacuum-assisted closure for sternal wounds: a first-line therapeutic management approach. Plast Reconstr Surg. 2005 Sep 15;116(4):1035-40; discussion 1041-3.

Song DH, Wu LC, Lohman RF, Gottlieb LJ, Franczykm. Vacuum assisted closure for the treatment of sternal wounds: the bridge between debridement and definitive closure. Plastic and Reconstructive Surgery, 2003; 111(1): 92-97.

deLange MY, Schasfoort RA, Obdeijn MC, van Der Werff JFA, NicolaiJPA. Vacuum-assisted closure: indications and clinical experience. European Journal of Plastic Surgery. 2000 May;23(4):178-82.

DeFranzo AJ, Argenta LC, Marks MW, Molnar JA, David LR, Webb LX,Ward WG, Teasdall RG. The use of vacuum-assisted closure therapy forthe treatment of lower-extremity wounds with exposed bone. Plastic and Reconstructive Surgery. 2001 Oct;108(5):1184-91.

Gabriel A, Heinrich C, Shores JT, Baqai WK, Rogers FR, Gupta S. Reducing bacterial bioburden in infected wounds with vacuum assisted closure and a new silver dressing---a pilot study. Wounds. 2006 Sept: 18(9): 245-255.

 
Sternal Wounds
Song DH, Wu LC, Lohman RF, Gottlieb LJ, Franczyk KM. Vacuum assisted closure for the treatment of sternal wounds: the bridge between debridement and definitive closure. Plastic and Reconstructive Surgery, 2003; 111(1): 92-97.

Agarwal JP, Ogilvie M, Wu LC, Lohman RF, Gottlieb LJ, Franczyk M, Song DH. Vacuum-assisted closure for sternal wounds: a first-line therapeutic management approach. Plast Reconstr Surg. 2005 Sep 15;116(4):1035-40; discussion 1041-3.

Tang ATM, Ohri SK, Haw MP. Novel application of vacuum assisted closure technique to the treatment of sternotomy wound infection. European Journal of Cardio-Thoracic Surgery, 2000;17:482-4.

Orgill DP, Austen WG, Butler CE, Fine NA, Horvath KA, Mihaljevic T, Song DH, Wolfe WG. Guidelines for treatment of complex chest wounds with negative pressure wound therapy. Wounds. 2004 Dec;16(Suppl B): 1-23.
Partial-Thickness Burns
Molnar JA, DeFranzo AJ, Hadaegh A, Morykwas MJ, Shen P, Argenta LC. Acceleration of Integra incorporation in complex tissue defects with subatmospheric pressure. Plastic and Reconstructive Surgery. 2004 Apr15; 113(5): 1339-1346.
Skin Grafts
Moisidis E, Heath T, Boorer C, Ho K, Deva AK. A Prospective, Blinded, Randomized, Controlled Clinical Trial of Topical Negative Pressure Use in Skin Grafting. Plastic and Reconstructive Surgery. September 2004; 114(4): 917-922.

Repta R, Ford R, Hoberman L, Rechner B. The use of negative-pressure therapy and skin grafting in the treatment of soft-tissue defects over the achilles tendon. Ann Plast Surg. 2005 Oct;55(4):367-70.

Schneider AM, Morykwas MJ, Argenta LC. A new and reliable method ofsecuring skin grafts to the difficult recipient bed. Plastic and Reconstructive Surgery. 1998 Sep;102(4):1195-8.

DeFranzo AJ, Marks MW, Argenta LC, Genecov DG. Vacuum-Assisted Closure for the treatment of degloving injuries. Plastic and Reconstructive Surgery, 1999; 104(7): 2145-8.

Molnar JA, DeFranzo AJ, Hadaegh A, Morykwas MJ, Shen P, Argenta LC. Acceleration of Integra incorporation in complex tissue defects with subatmospheric pressure. Plastic and Reconstructive Surgery. 2004 Apr15; 113(5): 1339-1346.

Meara JG, Guo L, Smith JD, Pribaz JJ, Breuing KH, Orgill DP. Vacuum-Assisted Closure in the treatment of degloving injuries. Annals of Plastic Surgery, 1999; 42(6): 589-94.
Pressure Ulcer
Wu SH, Zecha PJ, Feitz R, Hovius SER. Vacuum therapy as an intermediate phase in wound closure: a clinical experience. European Journal of Plastic Surgery, 2000; 23: 174-7.

Joseph E, Hamori CA, Bergman S, Roaf E, Swann NF, Anastasi GW. A Prospective Randomized Trial of Vacuum-Assisted Closure Versus Standard Therapy of Chronic Nonhealing Wounds. WOUNDS; 12(2): 60-67.

Deva AK, Siu C, Nettle WJS. Vacuum-assisted closure of a sacral pressure sore. Journal of Wound Care.1997 July;6(7):311-2.

Tina Schwien, MN, MPH, Jeff Gilbert, MS, CPHIMS, and Christine Lang. Pressure Ulcer Prevalence and the Role of Negative Pressure Wound Therapy in Home Health Quality Outcomes. Ostomy Wound Management 2005; 51(9): 47-60.

Greer SE, Duthie E, Cartolano B, Koehler KM, Maydick-Youngberg D,Longaker MT. Techniques for applying subatmospheric pressure dressing to wounds in difficult regions of anatomy. Journal of Wound, Ostomy andContinence Nursing, 1999: 26(5): 250-3.

Gupta S, Baharestani M, Baranoski S, de Leon J, Engel SJ, Mendez-Eastman S, Niezgoda JA, Pompeo MQ. Guidelines for managing pressure ulcers with negative pressure wound therapy. Advances in Skin and Wound Care. 2004 Nov/Dec;17(Suppl 2):1-16.
 
Ortho Trauma Wounds
DeFranzo AJ, Argenta LC, Marks MW, Molnar JA, David LR, Webb LX, Ward WG, Teasdall RG. The use of vacuum-assisted closure therapy for the treatment of lower-extremity wounds with exposed bone. Plastic and Reconstructive Surgery. 2001Oct;108(5):1184-91.

deLange MY, Schasfoort RA, Obdeijn MC, van Der Werff JFA, NicolaiJPA. Vacuum-assisted closure: indications and clinical experience. European Journal of Plastic Surgery. 2000 May;23(4):178-82.

DeFranzo AJ, Marks MW, Argenta LC, Genecov DG. Vacuum-Assisted Closure for the treatment of degloving injuries. Plastic and ReconstructiveSurgery, 1999; 104(7): 2145-8.

Parrett BM, Matros E, Pribaz JJ, Orgill DP. Lower extremity trauma: trends in the management of soft-tissue reconstruction of open tibia-fibula fractures. Plastic and Reconstructive Surgery. 2006 Apr;117(4):1315-22; discussion 1323-4.

 
Diabetic Wounds
Page JC, Newswander B, Schwenke DC, Hansen M, Ferguson J. Retrospective analysis of negative pressure wound therapy in open foot wounds with significant soft tissue defects. Advances in Skin & Wound Care, 2004; 17(7): 354-364.

Armstrong DG, Attinger CE, Boulton AJM, Frykberg RG, Kirsner RS. Guidelines regarding negative pressure wound therapy (NPWT) in the diabetic foot: results of the Tucson expert consensus Conference (TECC) on V.A.C. therapy. Ostomy Wound Management, 2004 Apr;50(4 Suppl. B):3S-27S.

Andros G, Armstrong D, Attinger C, Boulton A, Frykberg R, Joseph W, Lavery L, Morbach S, Niezgoda J, Toursarkissian B. Consensus Statement on Negative Pressure Wound Therapy (V.A.C.® Therapy) for the Management of Diabetic Foot Wounds. Ostomy Wound Management. 2006 June; 52(6) Suppl.

 
Surgical Wounds
Morykwas MJ, Faler BJ, Pearce DJ, Argenta LC. Effects of varying levelsof subatmospheric pressure on the rate of granulation tissue formation in experimental wounds in swine. Annals of Plastic Surgery, 2001; 47(5):547-551.

Fabian TS, Kaufman HJ, Lett ED, Thomas JB, Rawl DK, Lewis PL,Summitt JB, Merryman JI, Schaeffer TD, Sargent LA, Burns RP. The evaluation of subatmospheric pressure and hyperbaric oxygen in ischemic full-thickness wound healing. The American Surgeon. 2000Dec;66(12):1136-43.

Yuan-Innes MJ, Temple CLF, Lacey MS. Vacuum-assisted wound closure: A new approach to spinal wounds with exposed hardware. Spine, 2001; 26(3):E30-33.

Bookout K, McCord S, McLane K. Case studies of an infant, a toddler, and an adolescent treated with a negative pressure wound treatment system. JWOCN, 2004; 31(4): 184-192.

Chantal M. Moues, et. al. An Economic Evaluation of the use of TNP on full-thickness wounds. Journal of Wound Care Vol. 14, NO 5, page 1-6 May 2005.

Meara JG, Guo L, Smith JD, Pribaz JJ, Breuing KH, Orgill DP. Vacuum-Assisted Closure in the treatment of degloving injuries. Annals of PlasticSurgery, 1999; 42(6): 589-94.

Bickels J, Kollender Y, Wittig J. Vacuum-assisted wound closure after resection of musculoskeletal tumors. Clinical Orthopaedics and Related Research. 2005 Dec; 441:346-50.